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JoVE Journal Developmental Biology
Uso del trapianto di cellule staminali ematopoietiche per valutare l'origine della sindrome Myelodysplastic
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Uso del trapianto di cellule staminali ematopoietiche per valutare l'origine della sindrome Myelodysplastic

Article DOI: 10.3791/58140-v • 06:39 min • October 3rd, 2018
October 3rd, 2018 •
1, 1, 2, 1
1Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 2LGI Flow Cytometry Core Facility, Center for Cancer Research, National Cancer Institute, National Institutes of Health

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Descriviamo l'uso del trapianto di cellule staminali ematopoietiche (HSCT) per valutare il potenziale maligno delle cellule emopoietiche geneticamente. HSCT è utile per valutare varie cellule ematopoietiche maligne in vivo , nonché generando un'ampia coorte di topi con sindromi mielodisplastiche (MDS) o leucemia per valutare nuove terapie.

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Biologia dello sviluppo problema 140 sindromi mielodisplastiche trapianto di cellule staminali ematopoietiche fluorescenza-attivato delle cellule ordinamento midollo osseo NUP98-HOXD13 leucemia mieloide acuta malignità ematopoietiche
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