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Journal / Bioengineering / 透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究…
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Bioengineering

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JoVE Journal Bioengineering
透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究
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透明质酸基水凝胶对3维患者源性胶质瘤细胞培养的研究

Article DOI: 10.3791/58176-v • 08:35 min • August 24th, 2018
August 24th, 2018 •
1, 1, 1, 2
1Department of Bioengineering, University of California, Los Angeles, 2Department of Bioengineering, Jonsson Comprehensive Cancer Center, Broad Stem Cell Research Center, Brain Research Institute, University of California, Los Angeles

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在这里, 我们提出了一个协议, 三维培养病人的胶质瘤细胞在正交可调谐生物材料设计, 以模仿大脑基质。这种方法提供了一种体外实验平台, 它能维持体内胶质瘤细胞的许多特征, 通常在培养中丢失。

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生物工程 138 期 透明质酸 3D 培养 胶质瘤 微环境 细胞外基质 生物材料 美国匹茨堡 耐药性
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