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Journal / Bioengineering / Hyaluronsyra baserat hydrogeler för…
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JoVE Journal Bioengineering
Hyaluronsyra baserat hydrogeler för 3-dimensionell kultur av patientderiverade Glioblastoma celler
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Hyaluronsyra baserat hydrogeler för 3-dimensionell kultur av patientderiverade Glioblastoma celler

Article DOI: 10.3791/58176-v • 08:35 min • August 24th, 2018
August 24th, 2018 •
1, 1, 1, 2
1Department of Bioengineering, University of California, Los Angeles, 2Department of Bioengineering, Jonsson Comprehensive Cancer Center, Broad Stem Cell Research Center, Brain Research Institute, University of California, Los Angeles

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Här presenterar vi ett protokoll för tredimensionella kultur av patientderiverade glioblastoma celler inom ortogonalt avstämbara biomaterial utformade för att efterlikna hjärnans matrisen. Detta tillvägagångssätt ger en in vitro-, Experimentell plattform som underhåller många egenskaper i vivo glioblastoma celler normalt förlorade i kultur.

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Bioteknik fråga 138 hyaluronsyra 3D kultur glioblastom närmiljön extracellulär matrix biomaterial Mekanobiologi läkemedelsresistens
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