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Immunology and Infection

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Dynamisk friktionskoefficient Assay for den funktionelle analyse af anti-friktion behandlinger i inflammatorisk tarmsygdom

Article DOI: 10.3791/58210-v • 08:27 min • September 20th, 2018
September 20th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1, 1
1Department of Medicine 1, University of Erlangen-Nuremberg

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Dynamisk vedhæftning af immunceller til karvæggen er en forudsætning for gut målsøgende. Her præsenterer vi en protokol til en funktionel i vitro assay for konsekvensanalyse af anti-integrin antistoffer, kemokiner eller andre faktorer på den dynamiske celle vedhæftning af menneskelige celler ved hjælp af addressin-belagt kapillærer.

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Immunologi og infektion sag 139 celle vedhæftning Integra addressin gut homing vedolizumab natalizumab
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