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Neuroscience

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在培养的小鼠神经元中可视化轴突生长锥塌陷和早期淀粉样β效应
 
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在培养的小鼠神经元中可视化轴突生长锥塌陷和早期淀粉样β效应

Article DOI: 10.3791/58229-v 06:23 min October 30th, 2018
October 30th, 2018

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Summary

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本文介绍了一种研究淀粉样蛋白β (Aβ) 在脑内早期作用的实验方案。 这表明 Aβ诱导网格蛋白介导的内吞和轴突生长锥的崩溃。该协议有助于研究 Aβ对轴突生长锥的早期影响, 并可促进预防阿尔茨海默病。

Tags

神经科学 问题 140 淀粉样β 轴突 生长锥 塌陷 内吞 活细胞成像
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