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Journal / Bioengineering / Brug af høj overførselshastighed automatiseret…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Brug af høj overførselshastighed automatiseret Microbioreactor System for produktion af Model IgG1 i CHO celler
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Brug af høj overførselshastighed automatiseret Microbioreactor System for produktion af Model IgG1 i CHO celler

Article DOI: 10.3791/58231-v • 08:15 min • September 28th, 2018
September 28th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1, 1
1Center for Drug Evaluation and Research, Office of Product Quality, Office of Biotechnology Products, Division of Biotechnology Review and Research II, U.S. Food and Drug Administration

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En detaljeret protokol for samtidige gennemførelsen af 48 parallelle cellekulturer under varierede forhold i et microbioreactor system er præsenteret. Celle kultur proces, høst og efterfølgende antistof titer analyse er beskrevet.

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Bioteknologi sag 139 mikro-bioreaktor kinesisk Hamster ovarie celler celle kultur Screening Glycans monoklonalt antistof størrelse udstødelse kromatografi multi-vinkel lysspredning.
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