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Journal / Cancer Research / 一种检测慢性淋巴细胞白血病新 nfat2…
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Cancer Research

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JoVE Journal Cancer Research
一种检测慢性淋巴细胞白血病新 nfat2 靶基因的染色质免疫沉淀法
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一种检测慢性淋巴细胞白血病新 nfat2 靶基因的染色质免疫沉淀法

Article DOI: 10.3791/58270-v • 09:52 min • December 4th, 2018
December 4th, 2018 •
1, 1, 1, 1, 2, 1, 1, 1, 1, 1
1Dept. of Hematology, Oncology and Immunology, University of Tübingen, 2Dept. of Endocrinology, Diabetology, Clinical Pathology and Metabolism, University of Tübingen

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慢性淋巴细胞白血病 (cll) 是西方世界最常见的白血病。nfat 转录因子是多种细胞类型发育和激活的重要调节剂。在这里, 我们提出了一个在人的 cll 细胞中使用染色质免疫沉淀 (chip) 来识别 nfat2 的新靶向基因的协议。

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癌症研究 第142期 cll nfat 转录因子 靶基因 启动子 染色质免疫沉淀
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