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Journal / Immunology and Infection / Antigene Liposomer for Generation af…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Antigene Liposomer for Generation af sygdoms-specifikke antistoffer
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Antigene Liposomer for Generation af sygdoms-specifikke antistoffer

Article DOI: 10.3791/58285-v • 10:31 min • October 25th, 2018
October 25th, 2018 •
*1, *2,3, *3,4, 5, 6, 3,4, 5,7
1Janssen R&D, 2Department of Microbiology and Immunology, University of North Carolina, 3UNC Food Allergy Initiative, University of North Carolina, 4Department of Pediatrics, University of North Carolina, 5Department of Chemistry, University of Alberta, 6Department of Molecular Medicine, Scripps Research Institute, 7Department of Medical Microbiology and Immunology, University of Alberta
* These authors contributed equally

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Beskrevet er forberedelsen af antigene liposomal nanopartikler og deres anvendelse i stimulerende B-celle aktivering i in vitro og i vivo. Sammenhængende og robust antistof svar førte til udviklingen af en ny jordnøddeallergi model. Protokol til at generere antigene Liposomer kan udvides til at omfatte forskellige antigener og immunisering modeller.

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Immunologi og infektion spørgsmål 140 nanopartikler Liposomer anafylaksi Peanut allergi Calcium Flux Flow flowcytometri Antigen specifikke Ara h 2 fødevareallergi IgE
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