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Journal / Immunology and Infection / Liposomas antigénicos para la generación de…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Liposomas antigénicos para la generación de anticuerpos específicos de la enfermedad
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Liposomas antigénicos para la generación de anticuerpos específicos de la enfermedad

Article DOI: 10.3791/58285-v • 10:31 min • October 25th, 2018
October 25th, 2018 •
*1, *2,3, *3,4, 5, 6, 3,4, 5,7
1Janssen R&D, 2Department of Microbiology and Immunology, University of North Carolina, 3UNC Food Allergy Initiative, University of North Carolina, 4Department of Pediatrics, University of North Carolina, 5Department of Chemistry, University of Alberta, 6Department of Molecular Medicine, Scripps Research Institute, 7Department of Medical Microbiology and Immunology, University of Alberta
* These authors contributed equally

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Descrito es la preparación de nanopartículas liposómicos antigénicas y su uso en estimular la activación de células B en vitro e in vivo. Respuestas de anticuerpos consistente y robusto condujeron al desarrollo de un nuevo modelo de la alergia del cacahuete. El protocolo para la generación de liposomas antigénicas puede ampliarse a los diferentes antígenos y vacunas.

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Inmunología e infección número 140 nanopartículas liposomas anafilaxia alergia del cacahuete flujo de calcio citometría de flujo antígeno específico Ara h 2 alergia IgE
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