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Induksjon av aterosklerotisk plaketter gjennom aktivering av Mineralocorticoid reseptorer i Apolipoprotein E-mangelfull mus
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Induksjon av aterosklerotisk plaketter gjennom aktivering av Mineralocorticoid reseptorer i Apolipoprotein E-mangelfull mus

Article DOI: 10.3791/58303-v • 07:36 min • September 26th, 2018
September 26th, 2018 •
1, 1, 1, 1, 1,2
1Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Rome, Italy, 2Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy

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Vi beskriver en protokoll for å indusere aterosklerose i aorta roten av ApoE- / - mus med en atherogenic kosthold, gjennom en kontinuerlig utgivelsen av aldosteron. Metoder for å karakterisere plakk sammensetning er også beskrevet.

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Medisin problemet 139 Atherosclerosis aldosteron betennelse ApoE- / - aorta roten immunohistochemistry
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