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Journal / Chemistry / 用于靶向质粒DNA输送的美聚氨酸功能化生物相容性块共聚物…
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用于靶向质粒DNA输送的美聚氨酸功能化生物相容性块共聚物
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用于靶向质粒DNA输送的美聚氨酸功能化生物相容性块共聚物

Article DOI: 10.3791/58527-v • 08:09 min • August 6th, 2019
August 6th, 2019 •
*1, *2, 2, 3, 2, 3, 1, 2
1Research Center of Clinical Oncology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, 2Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, 3School of Clinical Medicine, Xuzhou Medical University
* These authors contributed equally

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本作品通过可逆添加-碎片链转移(RAFT)方法介绍了蛋氨酸功能化生物相容性块共聚物(mBG)的制备。研究了获得mBG的质粒DNA复合能力及其转染效率。RAFT方法对聚合含有特殊功能组的单体非常有益。

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化学 问题 150 可逆添加-碎片链转移 RAFT 药物输送系统 DDS 蛋氨酸 瓜尼丁 N-(3-氨基丙烯酰) 盐酸甲酰胺 APMA N,N-bis(2-羟基苯甲酸酯)甲酰胺 BNHEMA
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