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Metionin funktionaliserade biokompatibla Blocksampolymerer för riktad plasmid DNA-leverans
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Metionin funktionaliserade biokompatibla Blocksampolymerer för riktad plasmid DNA-leverans

Article DOI: 10.3791/58527-v • 08:09 min • August 6th, 2019
August 6th, 2019 •
*1, *2, 2, 3, 2, 3, 1, 2
1Research Center of Clinical Oncology, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, 2Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, 3School of Clinical Medicine, Xuzhou Medical University
* These authors contributed equally

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Detta arbete presenterar utarbetandet av metionin funktionaliserade biokompatibla block sampolymerer (MBG) via reversibel addition-fragmentering Chain Transfer (RAFT) metod. Den plasmid-DNA-komplexbildare förmågan hos de erhållna MBG och deras verkningsgrad undersöktes också. FLOTTE metoden är mycket fördelaktigt för polymeriserande monomerer som innehåller särskilda funktionella grupper.

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