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Neuroscience

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Ensayo basado en células para estudiar despacho Tau anticuerpo-mediada por la microglía

Article DOI: 10.3791/58576-v • 07:18 min • November 9th, 2018
November 9th, 2018 •
1, 2,3, 3, 3, 4, 3
1Neuroscience Discovery, Janssen Pharmaceutical Company of Johnson & Johnson, Belgium, 2Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, The Netherlands, 3Janssen Prevention Center, Janssen Pharmaceutical Company of Johnson & Johnson, The Netherlands, 4Neuroscience Discovery, Janssen Pharmaceutical Company of Johnson & Johnson, Pennsylvania

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Aquí describimos un ensayo basado en células para evaluar cuantitativamente la absorción tau por microglia con el objetivo de crear una herramienta de investigación para caracterizar mejor los mecanismos de acción de los anticuerpos anti-tau.

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Neurociencia número 141 Alzheimer tauopathy tau agregación microglia BV-2 absorción separación.
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