Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Engineering / Berige og udvide sjældne Antigen-specifikke…
JoVE Journal
Engineering

A subscription to JoVE is required to view this content.

JoVE Journal Engineering
Berige og udvide sjældne Antigen-specifikke T-celler med magnetisk nanopartikler
Gray Binarization of Concrete Image Sample
Journal (Engineering)
Gray Binarization of Concrete Image Sample
Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices
Journal (Engineering)
Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices
 
Click here for the English version

Berige og udvide sjældne Antigen-specifikke T-celler med magnetisk nanopartikler

Article DOI: 10.3791/58640-v • 09:28 min • November 17th, 2018
November 17th, 2018 •
1,2,3,4, 2,4
1Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, 2Institute for Cell Engineering, School of Medicine, Johns Hopkins University, 3Institute for Nanobiotechnology, Johns Hopkins University, 4Department of Pathology, School of Medicine, Johns Hopkins University

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Antigen-specifikke T-celler er vanskeligt at karakterisere eller udnytte på terapier på grund af deres ekstremt lavfrekvente. Heri, giver vi en protokol for at udvikle en magnetisk partikel, som kan binde sig til antigen-specifikke T-celler til at berige disse celler og derefter at udvide dem flere hundred-fold til både karakterisering og terapi.

Tags

Engineering sag 141 nanopartikler magnetiske berigelse kunstige antigen-præsenterer celler T-celler immunterapi kræft sjældne celle berigelse T-celle ekspansion adoptiv T-celleterapi Neoantigen immunoengineering bioteknologi
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter