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Journal / Genetics / qKAT: Quantitative Semi-automated Typing of…
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Genetics

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qKAT: Quantitative Semi-automated Typing of Killer-cell Immunoglobulin-like Receptor Genes

Article DOI: 10.3791/58646-v • 07:58 min • March 6th, 2019
March 6th, 2019 •
1,2,3,4, 1, 1,5, 1,6, 1,7, 1
1Department of Pathology, University of Cambridge, 2Department of Physiology, Development and Neuroscience, University of Cambridge, 3Department of Obstetrics and Gynaecology, University of Cambridge School of Medicine, NIHR Cambridge Biomedical Research Centre, 4Centre for Trophoblast Research, University of Cambridge, 5Department of Genetics & Evolution, University of Geneva, 6Royal Papworth Hospital, 7Department of Plant Sciences, University of Cambridge

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Summary
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Quantitative killer cell immunoglobulin-like receptor (KIR) semi-automated typing (qKAT) is a simple, high-throughput, and cost-effective method to copy number type KIR genes for their application in population and disease association studies.

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QKAT Quantitative Semi-automated Typing Killer-cell Immunoglobulin-like Receptor Genes NK Cell Receptor Genetics Haplotype Diversity Disease Association Automation Process Data Analysis High-throughput Gene Copy Number Viral Infections HIV Hepatitis C Cancer Stem Cell Transplantation Pregnancy Disorders Population Genetics Expression Functional Interactions Exons Multiplex Reactions Specific Primers PCR Amplification Real Time Monitoring Copy Number Analysis
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