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Ein Rhodopsin Transport Test von High-Content Imaging-Analyse
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Ein Rhodopsin Transport Test von High-Content Imaging-Analyse

Article DOI: 10.3791/58703-v • 12:11 min • January 16th, 2019
January 16th, 2019 •
1, 1, 1,2
1Department of Ophthalmology, University of Pittsburgh, 2McGowan Institute for Regenerative Medicine, University of Pittsburgh

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Wir beschrieben hier, ein High-Content bildgebendes Verfahren zur Quantifizierung des Transports von Rhodopsin Mutanten mit Retinitis Pigmentosa verbunden. Eine Multiple-Wellenlänge scoring Analyse wurde zur Rhodopsin Proteine auf der Zelloberfläche oder in der ganzen Zelle zu quantifizieren.

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Chemie Ausgabe 143 High-Content imaging misfolded Protein Rhodopsin Retinitis Pigmentosa pharmakologische Chaperon immunostaining
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