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Journal / Genetics / Candida albicans insan mantar patojen genom…
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Genetics

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JoVE Journal Genetics
Candida albicans insan mantar patojen genom düzenleme CRISPR-aracılı
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Candida albicans insan mantar patojen genom düzenleme CRISPR-aracılı

Article DOI: 10.3791/58764-v • 09:56 min • November 14th, 2018
November 14th, 2018 •
*1, *1, 2, 1
1Department of Biology, Ball State University, 2Whitehead Institute for Biomedical Research
* These authors contributed equally

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Candida albicans verimli genom mühendislik patogenez ve tedavi gelişimini anlamak için önemlidir. Burada, hızlı ve doğru CRISPR kullanarak C. albicans genom düzenlemek için bir iletişim kuralı açıklanan. Protokol müfettişler çok çeşitli noktasını mutasyonlar, eklemeler ve silmeler dahil olmak üzere genetik değişiklik tanıtmak sağlar.

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Genetik sayı: 141 CRISPR Candida albicans düzenleme dönüştürme Cas9 patojen mantarlar genom
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