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Journal / Neuroscience / Kinnet injeksjon modell for samtidig måling av…
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Neuroscience

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JoVE Journal Neuroscience
Kinnet injeksjon modell for samtidig måling av smerte og kløe-relaterte atferd
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Kinnet injeksjon modell for samtidig måling av smerte og kløe-relaterte atferd

Article DOI: 10.3791/58943-v • 04:59 min • September 27th, 2019
September 27th, 2019 •
1,2,3,4, 1,2,5, 1,2,3,6
1Thermal Biology Group, Exploratory Research Center on Life and Living Systems (ExCELLS), 2Division of Cell Signaling, National Institute for Physiological Sciences, 3Department of Physiological Sciences, Graduate University for Advanced Studies (SOKENDAI), 4Research Laboratory, Ikedamohando Co., Ltd., 5Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 6Institute for Environmental and Gender-Specific Medicine, Juntendo University

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Vanligvis brukes musen nakke injeksjon modellen for å evaluere pruritogen-indusert scratch atferd. Men modellen gir informasjon bare på kløe, ikke smerte. Her er en kinn injeksjon modell innført i mus som kan brukes til å samtidig måle smerte og kløe-relatert atferd.

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Nevrovitenskap skrape kløe smerte atferd histamin capsaicin
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