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Immunology and Infection

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JoVE Journal Immunology and Infection
En musemodel at vurdere medfødte immunrespons for Staphylococcus aureus infektioner
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En musemodel at vurdere medfødte immunrespons for Staphylococcus aureus infektioner

Article DOI: 10.3791/59015-v • 09:15 min • February 28th, 2019
February 28th, 2019 •
1, 1, 1, 2, 1
1Department of Biomedical Engineering, University of California Davis, 2Department of Dermatology, Johns Hopkins University School of Medicine

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En tilgang er beskrevet til real-time opdagelse af medfødte immun respons til kutane såret og Staphylococcus aureus infektion af mus. Ved at sammenligne LysM-EGFP mus (som besidder fluorescerende neutrofiler) med en LysM-EGFP krydset immundefekte mus stamme, vi fremme vores forståelse af infektion og udvikling af metoder til at bekæmpe infektion.

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Immunologi og infektion spørgsmålet 144 Staphylococcus aureus medfødt immunitet neutrofiler sårheling inflammation hele dyr imaging
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