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Costruzione efficiente di Drug-like Bispirocyclic ponteggi Via ORGANOCATALISI CICLOADDIZIONI di α-immino γ-lattoni e alchilidene pirazolone
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Costruzione efficiente di Drug-like Bispirocyclic ponteggi Via ORGANOCATALISI CICLOADDIZIONI di α-immino γ-lattoni e alchilidene pirazolone

Article DOI: 10.3791/59155-v • 10:17 min • February 7th, 2019
February 7th, 2019 •
1, 2, 2, 2
1School of Basic Medical Sciences, Lanzhou University, 2School of Pharmaceutical Sciences, Sun Yat-sen University

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Bispiro enantiomericamente arricchita [γ-butirrolattone-pyrrolidin-4, 4'-della pirazolone] scheletri asimmetricamente sono sintetizzati attraverso una reazione di cicloaddizione 1,3-dipolare ORGANOCATALISI semplice.

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Chimica problema 144 sintesi asimmetrica KBR composti bispirocyclic cicloaddizione lattoni pirazolone
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