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Construção eficiente de andaimes de drogas, como Bispirocyclic Via Organocatalytic cicloadições de γ-lactonas α-Imino e pirazolonas Alkylidene
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Construção eficiente de andaimes de drogas, como Bispirocyclic Via Organocatalytic cicloadições de γ-lactonas α-Imino e pirazolonas Alkylidene

Article DOI: 10.3791/59155-v • 10:17 min • February 7th, 2019
February 7th, 2019 •
1, 2, 2, 2
1School of Basic Medical Sciences, Lanzhou University, 2School of Pharmaceutical Sciences, Sun Yat-sen University

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Bispiro enantiomerically enriquecido [γ-butirolactona-pyrrolidin-4, 4'-zolone] esqueletos assimetricamente são sintetizados através de uma reação de cicloadição 1,3-dipolar de organocatalytic simples.

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Química questão 144 síntese assimétrica organocatalysis bispirocyclic compostos cicloadição lactonas pirazolonas
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