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JoVE Journal Neuroscience
Direkte indsprøjtning af en Lentiviral vektor fremhæver flere Motor veje i rygmarven rotte
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Direkte indsprøjtning af en Lentiviral vektor fremhæver flere Motor veje i rygmarven rotte

Article DOI: 10.3791/59160-v • 07:57 min • March 15th, 2019
March 15th, 2019 •
1, 1, 1, 1, 1
1Shriner's Pediatric Research Center, Temple University

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Denne protokol viser injektion af en retrogradely transportable viral vektor i rotte rygmarv væv. Vektor er taget på synapser og transporteres til cellen kroppen af target neuroner. Denne model er velegnet til retrograd sporing af vigtige spinal stier eller målretning celler for gen terapi programmer.

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Neurovidenskab sag 145 viral vektor retrograd sporing rygmarven injektion lentivirus genterapi neurovidenskab
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