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JoVE Journal Bioengineering
Chemoattractant degradelere Multi-hücresel tepkiler 3D Analizi
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Chemoattractant degradelere Multi-hücresel tepkiler 3D Analizi

Article DOI: 10.3791/59226-v • 05:57 min • May 24th, 2019
May 24th, 2019 •
1, 2, 1, 2,3, 1
1Department of Biomedical Engineering and Yale Systems Biology Institute, Yale University, 2Department of Biomedical Engineering, Johns Hopkins University, 3Center for Cell Dynamics and Department of Cell Biology, Johns Hopkins University

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Biz 3D kültür ve hücreler ve çok hücreli organoids ile deney için cihazlar oluşturmak için bir yöntem açıklanmaktadır. Bu cihaz, tanımlanan kemoçekici degradeler ile 3D mikro ortamlarda çözünür sinyallere hücresel tepkiler analizi sağlar. Organoids zayıf gürültülü girişleri tespiti tek hücrelerden daha iyidir.

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Biyomühendislik sayı 147 gradyan algılama organ-on-a-çip chemotaxis stereolitografi ekstrüde matris geliştirme organoids
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