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Journal / Cancer Research / I Vitro svulst celle Rechallenge For prediktiv…
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Cancer Research

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JoVE Journal Cancer Research
I Vitro svulst celle Rechallenge For prediktiv evaluering av Chimeric Antigen reseptor T celle Antitumor funksjon
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I Vitro svulst celle Rechallenge For prediktiv evaluering av Chimeric Antigen reseptor T celle Antitumor funksjon

Article DOI: 10.3791/59275-v • 08:04 min • February 27th, 2019
February 27th, 2019 •
1,2, 1, 1, 1, *1, *1
1Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute and Medical Center
* These authors contributed equally

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Her beskriver vi en i vitro co kultur metode rekursivt utfordring svulst målrettede T celler, som tillater fenotypiske og funksjonell analyse av antitumor T celle aktivitet.

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Kreftforskning problemet 144 immunterapi adopsjon celle overføring co kultur analysen effektor styrke langsiktig funksjon t celle utmattelse
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