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Journal / Cancer Research / Em Vitro Tumor Cell reexposição para avaliação…
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Cancer Research

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JoVE Journal Cancer Research
Em Vitro Tumor Cell reexposição para avaliação preditiva de Receptor de antígeno quimérico célula T função antitumoral
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Em Vitro Tumor Cell reexposição para avaliação preditiva de Receptor de antígeno quimérico célula T função antitumoral

Article DOI: 10.3791/59275-v • 08:04 min • February 27th, 2019
February 27th, 2019 •
1,2, 1, 1, 1, *1, *1
1Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute and Medical Center
* These authors contributed equally

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Aqui, descrevemos um método in vitro co-cultura para recursivamente desafio tumor-alvo as células T, que permite a análise fenotípica e funcional da atividade antitumoral de célula T.

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Cancer Research edição 144 imunoterapia transferência adotiva de células ensaio de co-cultura potência effector função a longo prazo exaustão de célula t
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