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In vivo hemming av MicroRNA å redusere tumor vekst i mus
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In vivo hemming av MicroRNA å redusere tumor vekst i mus

Article DOI: 10.3791/59322-v • 07:02 min • August 23rd, 2019
August 23rd, 2019 •
1,2, 1, 1,2, 1,2, 1,2
1Instituto de Investigaciones Biomédicas, CSIC-UAM, 2Ciberonc, Instituto de Salud Carlos III

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Denne protokollen beskriver xenograft og orthotopic musemodeller av Human thyroid tumorigenesis som en plattform for å teste microRNA-baserte inhibitor behandlinger. Denne tilnærmingen er ideell for å studere funksjonen av ikke-koding RNAs og deres potensial som nye terapeutiske mål.

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Kreftforskning miRNA inhibitor skjoldbruskkjertelen tumor vekst mus modeller miRNA-basert behandling miR-146b thyroid kreft
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