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Developmental Biology

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JoVE Journal Developmental Biology
En in vitro 3D-model og beregnings ledning til kvantificering af det Vasculogeniske potentiale af iPSC-afledte Endotelafprogenitorer
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En in vitro 3D-model og beregnings ledning til kvantificering af det Vasculogeniske potentiale af iPSC-afledte Endotelafprogenitorer

Article DOI: 10.3791/59342-v • 06:36 min • May 13th, 2019
May 13th, 2019 •
1, 1
1Department of Biomedical Engineering, University of Texas at Austin

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Endotheliale progenitorer afledt af inducerede pluripotente stamceller (iPSC-EPs) har potentialet til at revolutionere kardiovaskulære sygdoms behandlinger og gøre det muligt at skabe mere trofaste kardiovaskulære sygdomsmodeller. Heri beskrives indkapsling af iPSC-EPs i tredimensionale (3D) kollagenmikromiljøer og en kvantitativ analyse af disse cellers vasculogeniske potentiale.

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Udviklingsmæssige biologi stamcelle endotel stamfader vasculogenesis ekstracellulær matrix kollagen beregningsmæssige analyse fartøjs netværk
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