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Journal / Developmental Biology / I Vitro Generation av Somite derivat från…
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Developmental Biology

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JoVE Journal Developmental Biology
I Vitro Generation av Somite derivat från mänskliga inducerade stamceller pluripotenta
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I Vitro Generation av Somite derivat från mänskliga inducerade stamceller pluripotenta

Article DOI: 10.3791/59359-v • 06:21 min • April 25th, 2019
April 25th, 2019 •
1, 2, 2
1Department of Life Science Frontiers, Center for iPS Cells Research and Application, Kyoto University, 2Department of Clinical Application, Center for iPS Cells Research and Application, Kyoto University

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Vi presenterar här ett protokoll för differentiering av mänskliga inducerade pluripotenta stamceller i varje somite derivat (myotome, sclerotome, Dermatom och syndetome) i kemiskt definierade förhållanden, som har tillämpningar inom framtida sjukdom modellering och cellbaserade terapier i ortopedisk kirurgi.

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Utvecklingsbiologi fråga 146 inducerade pluripotenta stamceller differentiering paraxiala mesoderm somite myotome sclerotome Dermatom syndetome
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