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Journal / Cancer Research / Forudsigelse i Vivo nyttelast levering ved hjælp…
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Cancer Research

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JoVE Journal Cancer Research
Forudsigelse i Vivo nyttelast levering ved hjælp af en blod-hjerne Tumor barriere i et fad
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Forudsigelse i Vivo nyttelast levering ved hjælp af en blod-hjerne Tumor barriere i et fad

Article DOI: 10.3791/59384-v • 13:34 min • April 16th, 2019
April 16th, 2019 •
1, 1,2, 1,3
1Research Programs Unit, Translational Cancer Medicine Research Program, University of Helsinki, 2Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 3Laboratory Animal Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki

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Drug målretning til centralnervesystemet tumorer er en stor udfordring. Her beskriver vi en protokol for at producere en in vitro-efterligner af blod-hjerne tumor-barrieren ved hjælp af murine og/eller menneskelige celler og diskutere deres relevans for forudsigelighed af centralnervesystemet tumor målretning in vivo.

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Kræftforskning spørgsmålet 146 blod-hjerne tumor-barriere glioblastom intercellulære transport in vivo billeddannelse nanopartikler endotel permeabilitet CooP peptid tumor målretning co kulturer astrocytter endotel Celledifferentiering
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