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Journal / Developmental Biology / Ex Vivo Perfusion der Rodent Placenta
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Developmental Biology

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JoVE Journal Developmental Biology
Ex Vivo Perfusion der Rodent Placenta
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Ex Vivo Perfusion der Rodent Placenta

Article DOI: 10.3791/59412-v • 06:54 min • May 30th, 2019
May 30th, 2019 •
1, 2, 1,2
1Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, 2Environmental and Occupational Health Sciences Institute

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Hier wird ein Protokoll der ex vivo mütterlich-fetalen Gefäßperfusion vorgestellt, um die Verabreichung eines Testartikels in die mütterliche Vaskulatur zu ermöglichen und die plazentale Übertragung von xenobiotischen Partikeln oder pharmakologischen Wirkstoffen zu bewerten, zusätzlich zu den Veränderungen in Plazentale Physiologie.

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Entwicklungspubologie Ausgabe 147 Plazenta Perfusion xenobiotischer Transfer technisches Nanomaterial Plazenta-Pharmakokinetik fetale Exposition
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