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Ex Vivo ekspansion af hæmatopoietisk stamceller fra menneskelige navlestrengen blod-afledte CD34+ celler ved hjælp af valproinsyre
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Ex Vivo ekspansion af hæmatopoietisk stamceller fra menneskelige navlestrengen blod-afledte CD34+ celler ved hjælp af valproinsyre

Article DOI: 10.3791/59532-v • 10:42 min • April 11th, 2019
April 11th, 2019 •
1, 1, 1
1Division of Hematology/Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai

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Her, vi beskrive ex vivo ekspansion af hæmatopoietisk stamceller fra CD34+ celler, der stammer fra navlestrengsblod behandlet med en kombination af en cytokin cocktail og VPA. Denne metode fører til en betydelig grad af ex vivo ekspansion af primitive HSCs for enten klinisk eller laboratorium applikationer.

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Medicin spørgsmål 146 navlestrengsblod CD34+ celler ex vivo kultur VPA HSCs ex vivo ekspansion transplantation genterapi
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