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Journal / Developmental Biology / Bestemmelse galdegang tæthed i muse leveren
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Developmental Biology

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JoVE Journal Developmental Biology
Bestemmelse galdegang tæthed i muse leveren
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Bestemmelse galdegang tæthed i muse leveren

Article DOI: 10.3791/59587-v • 07:35 min • April 30th, 2019
April 30th, 2019 •
1,2,3, 1,3
1Program in Developmental Biology, Baylor College of Medicine, 2Medical Scientist Training Program (MSTP), Baylor College of Medicine, 3Department of Molecular and Human Genetics, Baylor College of Medicine

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Vi præsenterer en temmelig enkel og følsom metode til nøjagtig kvantificering af galdegang tæthed i muse leveren. Denne metode kan hjælpe med at bestemme virkningerne af genetiske og miljømæssige modifikatorer og effektiviteten af potentielle terapier i musemodeller af Biliære sygdomme.

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Udviklingsmæssige biologi lever udvikling galdegang cytokeratin notch signalering Alagille syndrom Jag1
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