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Usando CRISPR/Cas9 para knock out GM-CSF em células CAR-T
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Usando CRISPR/Cas9 para knock out GM-CSF em células CAR-T

Article DOI: 10.3791/59629-v • 07:56 min • July 22nd, 2019
July 22nd, 2019 •
1,2, 3, 3, 2,3
1Mayo Clinic Medical Scientist Training Program, Mayo Clinic College of Medicine and Science, 2Department of Immunology, Mayo Clinic, 3Division of Hematology, Mayo Clinic

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Aqui, apresentamos um protocolo para editar geneticamente as células CAR-T através de um sistema CRISPR/Cas9.

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Pesquisa do cancro edição 149 célula T do receptor quimérico do antígeno pilha de CAR-T CRISPR/Cas9 edição do gene Knockout GM-CSF
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