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Journal / Medicine / En kanin model af vandig-mangelfuld tørre øjne…
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Medicine

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JoVE Journal Medicine
En kanin model af vandig-mangelfuld tørre øjne sygdom induceret af Concanavalin En injektion i lacrimal kirtler
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En kanin model af vandig-mangelfuld tørre øjne sygdom induceret af Concanavalin En injektion i lacrimal kirtler: Ansøgning til Drug Efficacy Studies

Article DOI: 10.3791/59631-v • 08:04 min • January 24th, 2020
January 24th, 2020 •
1, 2,3, 2
1Department of Ophthalmology, Stony Brook University, 2Department of Preventive Medicine, Stony Brook University, 3Medicon Pharmaceuticals, Inc.

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Denne artikel beskriver udviklingen af en metode til at fremkalde akut eller kronisk tør øjensygdom hos kaniner ved at injicere concanavalin A til alle dele af orbital lacrimal kirtel system. Denne metode, overlegen i forhold til dem, der allerede er rapporteret, genererer en reproducerbar, stabil model af tørre øjne egnet til studiet af farmakologiske midler.

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