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JoVE Journal
Genetics

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探索序列空间,识别调节RNA结合蛋白的结合位点
 
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探索序列空间,识别调节RNA结合蛋白的结合位点

Article DOI: 10.3791/59635-v 11:34 min August 9th, 2019
August 9th, 2019

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Summary

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Click here for the English version.

序列特异性对基因调控至关重要。识别特定序列的调控蛋白对基因调控非常重要。为这种蛋白质定义功能结合位点是一个具有挑战性的生物学问题。此处描述了一种用于识别RNA结合蛋白结合位点的迭代方法,适用于所有RNA结合蛋白。

Tags

遗传学 问题 150 RNA 结合蛋白 迭代选择扩增 拼接 聚丙胺-片位/3'拼接位点 SELEX 试管中的序列进化
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