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JoVE Journal Bioengineering
A Freeze-Thawing Method to Prepare Chitosan-Poly(vinyl alcohol) Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
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A Freeze-Thawing Method to Prepare Chitosan-Poly(vinyl alcohol) Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Article DOI: 10.3791/59636-v • 08:59 min • January 14th, 2020
January 14th, 2020 •
1, 2, 1
1Department of Polymers and Materials Research, University of Sonora, 2Department of Chemistry, Faculty of Sciences, University of Navarra

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Summary
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The freezing-thawing method is used to produce chitosan-poly(vinyl alcohol) hydrogels without crosslinking agents. For this method, it is important to consider the freezing conditions (temperature, number of cycles) and polymer ratio, which can affect the properties and applications of the obtained hydrogels.

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Freeze-thawing Method Chitosan-Poly(vinyl Alcohol) Hydrogels Biocompatible Hydrogels Pharmaceutical Applications Cosmetical Applications Chemical Crosslinking Agents Diflunisal Release Studies Freezing Condition Control Water Pollution Treatment Polymer Beads Production Homogenize Polymer Solution Cracking Points Chitosan Solution Preparation PVA Solution Preparation Petri Dishes
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