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Cancer Research

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JoVE Journal Cancer Research
Mikromanipulering av sirkulerende tumor celler for nedstrøms molekylær analyse og metastatisk potensiell vurdering
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Mikromanipulering av sirkulerende tumor celler for nedstrøms molekylær analyse og metastatisk potensiell vurdering

Article DOI: 10.3791/59677-v • 05:17 min • May 14th, 2019
May 14th, 2019 •
*1, *1, *1, 1,2, 1
1Cancer Metastasis Laboratory, Department of Biomedicine, University of Basel and University Hospital Basel, 2SIB Swiss Institute of Bioinformatics
* These authors contributed equally

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Her presenterer vi en integrert arbeidsflyt for å identifisere fenotypiske og molekylære funksjoner som karakteriserer sirkulerende tumorceller (CTC). Vi kombinerer Live immunostaining og Robotic mikromanipulering av singel og gruppert CTC med én celle-baserte teknikker for nedstrøms analyse og vurdering av metastasering-seeding evne.

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Kreftforskning sirkulerende tumorceller sirkulerende tumor celle klynger Mikromanipulering sirkulerende tumor cellekultur Single celle sekvenser metastasering brystkreft
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