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Journal / Cancer Research / 用于转化免疫肿瘤学(I-O)研究的人类外周血单核细胞(PBMC)的人工化异种移植模型…
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JoVE Journal Cancer Research
用于转化免疫肿瘤学(I-O)研究的人类外周血单核细胞(PBMC)的人工化异种移植模型
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用于转化免疫肿瘤学(I-O)研究的人类外周血单核细胞(PBMC)的人工化异种移植模型

Article DOI: 10.3791/59679-v • 08:17 min • August 15th, 2019
August 15th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1BeiGene (Beijing) Co., Ltd.
* These authors contributed equally

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我们描述了人类外周血单核细胞(PBMC)–基于人体的异种移植小鼠模型,用于转化免疫肿瘤学研究。该协议可作为建立和描述类似I-O治疗评估模型的一般准则。

Tags

回撤,第150期,免疫肿瘤学(I-O),外周血单核细胞(PBMC),Tislelizumab,BGB-A317,免疫缺陷,人性化,环磷酰胺(CP),患者衍生异种移植物(PDX)
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