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JoVE Journal Chemistry
Enzymatisk syntese af Epoxidiserede metabolitter af Docosahexaenoic, Eicosapentaenoic og arachidonsyre
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Enzymatisk syntese af Epoxidiserede metabolitter af Docosahexaenoic, Eicosapentaenoic og arachidonsyre

Article DOI: 10.3791/59770-v • 13:05 min • June 28th, 2019
June 28th, 2019 •
1, 1, 1, 1
1Department of Pharmacology and Toxicology, Michigan State University

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Vi præsenterer en metode, der er nyttig til storstilet enzymatisk syntese og rensning af specifikke enantiomerer og regioisomerer af Epoxider af arachidonsyre (AA), docosahexaensyre (DHA) og eicosapentaensyre Acid (EPA) med brug af en bakteriel cytokrom P450-enzym (BM3).

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Kemi epoxy flerumættede fedtsyrer lipider enzymatisk syntese enantioselektiv syntese Omega-3 fedtsyrer eicosanoider
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