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Journal / Biochemistry / 具有稳定的人类状古特微生物群落和人类免疫系统的双人性化BLT小鼠模型…
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Biochemistry

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JoVE Journal Biochemistry
具有稳定的人类状古特微生物群落和人类免疫系统的双人性化BLT小鼠模型
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具有稳定的人类状古特微生物群落和人类免疫系统的双人性化BLT小鼠模型

Article DOI: 10.3791/59773-v • 07:32 min • August 30th, 2019
August 30th, 2019 •
1,2, 1,2, 3, 1,2
1Nebraska Center for Virology, 2School of Biological Sciences, University of Nebraska-Lincoln, 3Department of Food Science and Technology, University of Nebraska-Lincoln

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我们描述了一种产生双重人性化BLT小鼠的新方法，其特点是功能性人体免疫系统和稳定的人类样肠道微生物群。无需无细菌小鼠或诺生物菌设施即可遵循此协议。

Tags

生物化学，第150期，双重人性化，BLT小鼠，肠道微生物群，免疫，抗生素，粪便移植
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