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JoVE Journal Neuroscience
Vurdering av lang tids depresjon induksjon i voksen lillehjernen skiver
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Vurdering av lang tids depresjon induksjon i voksen lillehjernen skiver

Article DOI: 10.3791/59859-v • 09:30 min • October 16th, 2019
October 16th, 2019 •
1, 2
1Laboratory for Behavioral Genetics, Center for Brain Science, RIKEN, 2Senior Adviser's Office, Center for Brain Science, RIKEN

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I noen genet-manipulert dyr, ved hjelp av en enkelt protokoll kan mislykkes i å indusere LTD i lillehjernen Purkinje celler, og det kan være et avvik mellom LTD og motor læring. Flere protokoller er nødvendig for å vurdere LTD-induksjon i genet-manipulert dyr. Standard protokoller vises.

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Nevrovitenskap Synaptic plastisitet LTD hjerne skive hele-celle-opptak mus Purkinje celle lillehjernen parallell fiber klatring fiber
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