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Presynapse dannelse analyse ved hjælp af Presynapse Organizer perler og "neuron Ball" kultur

Article DOI: 10.3791/59893-v • 10:17 min • August 2nd, 2019
August 2nd, 2019 •
1, 1, 1
1Functional Structure Biology Laboratory, Department of Medical Life Science, Yokohama City University Graduate School of Medical Life Science

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Presynapse dannelse er en dynamisk proces, herunder ophobning af synaptiske proteiner i ordentlig orden. I denne metode, presynapse dannelse udløses af perler konjugeret med en presynapse organisator protein på axonal plader af "neuron Ball" kultur, således at ophobning af synaptiske proteiner er let at blive analyseret under presynapse dannelse.

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Neurovidenskab presynapse LRRTM2 lokal oversættelse skrøbeligt X syndrom FMRP Munc18-1 aktiv zone excitatoriske synapse
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