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Modèle d'appendicectomie de Murine de cancer colorectal associé de colite chronique par localisation précise du patch caecal
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Modèle d'appendicectomie de Murine de cancer colorectal associé de colite chronique par localisation précise du patch caecal

Article DOI: 10.3791/59921-v • 08:51 min • August 24th, 2019
August 24th, 2019 •
1, 2,3, 1, 2,3, 1, 4, 1,5, 1,6, 1,2, 1
1Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, 2Institute of Medical Research, Northwestern Polytechnical University, 3School of Life Sciences, Northwestern Polytechnical University, 4Department of Medicine, Xi'an Jiaotong University, 5Princess Margaret Cancer Center, University of Health Network, 6Department of Pathology, Nanjing Medical University

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Le protocole présenté décrit un déplacement chirurgical facile de l'appendice (patch caecal) dans une souris suivie de l'induction du cancer colorectal associé à la maladie intestinale inflammatoire. Ce modèle d'appendicectomie de murine permet d'investigation du rôle biologique de l'appendice dans la pathogénie de la maladie gastro-intestinale humaine.

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Médecine Numéro 150 modèle murine appendice patch caecal anatomie gastro-intestinale gros intestin tumeur IgA azoxyméthane sulfate de dextran sodium MII
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