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Journal / Cancer Research / Using Human Induced Pluripotent Stem Cells for…
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Cancer Research

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Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells

Article DOI: 10.3791/59997-v • 10:57 min • October 24th, 2019
October 24th, 2019 •
*1,2, *1,2, 1,2, 1,2, 1, 3, 1,2
1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University
* These authors contributed equally

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Summary
Automatic Translation

This article describes a method to generate functional tumor antigen-specific induced pluripotent stem cell-derived CD8αβ+ single positive T cells using OP9/DLL1 co-culture system.

Tags

Human Induced Pluripotent Stem Cells Tumor Antigen-specific T Cells OP9-Delta-1 Co-culture System In Vitro T Cell Generation Regenerative Medicine Cell-based Therapies FBS Evaluation OP9-Delta-1 Cell Passage Cell Differentiation Senescence Surgical Oncology Fellow Human IPSC Colonies Human IPSC Media ROCK Inhibitor Cell Passaging Tool
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