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Journal / Immunology and Infection / Inmunoterapia adoptiva de células iNKT en ratones …
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Immunology and Infection

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JoVE Journal Immunology and Infection
Inmunoterapia adoptiva de células iNKT en ratones RA inducidos por glucosa-6-fosfato (G6PI)
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Inmunoterapia adoptiva de células iNKT en ratones RA inducidos por glucosa-6-fosfato (G6PI)

Article DOI: 10.3791/60048-v • 08:43 min • January 31st, 2020
January 31st, 2020 •
*1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2
1Medical School of Hebei University, 2Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Diseases in Hebei Province
* These authors contributed equally

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Este protocolo utiliza péptidos mixtos G6PI para construir modelos de artritis reumatoide que están más cerca de la artritis reumatoide humana en células CD4+ T y citoquinas. Células T asesinas naturales invariables de alta pureza (principalmente iNKT2) con fenotipos y funciones específicas se obtuvieron mediante inducción in vivo y purificación in vitro para inmunoterapia adoptiva.

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Inmunología e infección número 155 artritis reumatoide inmunoterapia adoptiva células iNKT citoquinas isomerasa de glucosa-6-fosfato (G6PI) sistema de imágenes in vivo (IVIS)
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