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Journal / Immunology and Infection / Immunoterapia adottiva delle cellule iNKT in…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Immunoterapia adottiva delle cellule iNKT in isomerasi indotta da glucosio (G6PI)
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Immunoterapia adottiva delle cellule iNKT in isomerasi indotta da glucosio (G6PI)

Article DOI: 10.3791/60048-v • 08:43 min • January 31st, 2020
January 31st, 2020 •
*1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2
1Medical School of Hebei University, 2Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Diseases in Hebei Province
* These authors contributed equally

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Questo protocollo utilizza peptidi misti G6PI per costruire modelli di artrite reumatoide che sono più vicini a quello dell'artrite reumatoide umana in CD4- cellule T e citochine. Cellule T killer naturali ad alta purezza (principalmente iNKT2) con fenotipi e funzioni specifiche sono state ottenute mediante induzione e purificazione in vitro per l'immunoterapia adottiva.

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Immunologia e infezione numero 155 artrite reumatoide immunoterapia adottiva cellule iNKT citochine isomerasa glucosio-6-fosfato (G6PI) sistema di imaging in vivo (IVIS)
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