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Journal / Immunology and Infection / Adoptiv immunterapi av iNKT-celler i…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Adoptiv immunterapi av iNKT-celler i glukos-6-fosfatisomeras (G6PI)-inducerad RA Möss
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Adoptiv immunterapi av iNKT-celler i glukos-6-fosfatisomeras (G6PI)-inducerad RA Möss

Article DOI: 10.3791/60048-v • 08:43 min • January 31st, 2020
January 31st, 2020 •
*1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2
1Medical School of Hebei University, 2Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Diseases in Hebei Province
* These authors contributed equally

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Detta protokoll använder G6PI blandade peptider för att konstruera reumatoid artrit modeller som är närmare den mänskliga reumatoid artrit i CD4+ T celler och cytokiner. Hög renhet invariant naturlig mördare T-celler (främst iNKT2) med specifika fenotyper och funktioner erhölls genom in vivo induktion och in vitro rening för adoptiv immunterapi.

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Immunologi och infektion reumatoid artrit adoptivimmunterapi iNKT-celler cytokiner glukos-6-fosfatisomeras (G6PI) in vivo imaging system (IVIS)
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