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Journal / Biology / Efflux pompaları Inhibisyonu Ile hematopoetik kök …
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Efflux pompaları Inhibisyonu Ile hematopoetik kök ve progenitor hücrelerde mitokondriyal membran potansiyelinin akış Cytometrik değerlendirilmesi doğruluğu iyileştirilmesi
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Efflux pompaları Inhibisyonu Ile hematopoetik kök ve progenitor hücrelerde mitokondriyal membran potansiyelinin akış Cytometrik değerlendirilmesi doğruluğu iyileştirilmesi

Article DOI: 10.3791/60057-v • 07:17 min • July 30th, 2019
July 30th, 2019 •
1,2,3, 1,2,3, 1,2,3,4
1Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, 2Departments of Cell Biology and Stem Cell Institute, Albert Einstein College of Medicine, 3Department of Medicine, Albert Einstein College of Medicine, 4Albert Einstein Cancer Center and Diabetes Research Center, Albert Einstein College of Medicine

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Xenobiotic "effluks" pompalar son derece hematopoetik kök ve progenitör hücreleri (hspcs) ve neden ekstrüzyon TMRM, bir mitokondriyal membran potansiyel floresan boya aktif. Burada, bir "effluks" pompa inhibitörü verapamil varlığında TMRM tarafından hspcs 'de mitokondriyal membran potansiyelini doğru ölçmek için bir protokol sunuyoruz.

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Biyoloji sayı 149 mitokondriyal membran potansiyeli hematopoetik kök hücre TMRM verapamil akış sitometri "effluks" pompaları çoklu ilaç direnci
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