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Journal / Immunology and Infection / Målrettet antistof blokering ved et dobbelt…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Målrettet antistof blokering ved et dobbelt funktionelt konjugat af antigene peptid og FC-III-Mimetika (DCAF)
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Målrettet antistof blokering ved et dobbelt funktionelt konjugat af antigene peptid og FC-III-Mimetika (DCAF)

Article DOI: 10.3791/60063-v • 09:39 min • September 17th, 2019
September 17th, 2019 •
*1,2, *3, 2, 2, 2, 3, 1,2
1Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 2Mass Spectrometry Core Facility, School of Life Sciences, Westlake University, 3MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University
* These authors contributed equally

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Udvikling af en dual-funktionelle konjugat af antigene peptid og FC-III MIME (DCAF) er en roman til eliminering af skadelige antistoffer. Her beskriver vi en detaljeret protokol for syntesen af DCAF1 molekyle, som selektivt kan blokere 4G2 antistof for at eliminere antistof afhængige ekstraudstyr effekt under dengue virus infektion.

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Retraktion DCAF målrettet terapi antistof Native Chemical ligation solid fase peptid syntese protein ekspression og rensning ELISA
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