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Immunology and Infection

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JoVE Journal Immunology and Infection
Mekanistisk Insight inn i utviklingen av TNBS-mediert intestinal fibrose og evaluere den hemmende effekten av Rapamycin
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Mekanistisk Insight inn i utviklingen av TNBS-mediert intestinal fibrose og evaluere den hemmende effekten av Rapamycin

Article DOI: 10.3791/60067-v • 10:21 min • September 12th, 2019
September 12th, 2019 •
1,2,3, 4, 4, 4, 1,2
1Department of Molecular and Cellular Physiology, Albany Medical College, 2The IBD Center, Division of Gastroenterology, Department of Medicine, Albany Medical College, 3Department of Geriatrics, School of Medicine and Health Science, University of North Dakota, 4Department of Neuroscience and Experimental Therapeutics, Albany Medical College

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I denne studien beskriver vi en detaljert prosedyre av TNBS-mediert tarm fibrose, som utstillinger sammenlignbare patofysiologi til Crohns fibrose. Vi diskuterer også denne tilnærmingen i lys av Rapamycin tilrettelagt hemmende effekter på intestinal fibrose.

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Immunologi og infeksjon TNBS-mediert intestinal fibrose Crohns sykdom betennelser Rapamycin autofagi bosatt macrophage genuttrykk
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